Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey

Xiao-Hua Zhang,Xiang-Dong Qing,Jing-Jing Zheng, Yan Yu, Jiaojiao Huang,Chao Kang,Zhi Liu

Food Chemistry: X（2023）

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摘要

•ATPS was first used to extract active components in honey.•A second-order calibration method for rapid quantitative analysis was developed.•The ATPS-ATLD-based method was developed for the first time.•Seven flavonoids can be accurately quantified within only 4.5 min.•The ATPS-ATLD-based method had the best performance than the classical SPE method.

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关键词

flavonoids,honey,simultaneous extraction,two-phase,chemometrics-enhanced,hplc-dad

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