408. Associations Between Area-Level Social Fragmentation During Childhood, Discrimination, and Lower Positive Core Schemas in Healthy Controls and Clinical High Risk for Psychosis Participants

Social fragmentation has been shown to be a strong predictor of psychosis onset. Less is known about how social fragmentation affects the development of brief core schemas among youth at clinical high risk for psychosis (CHR-P). We hypothesized that greater area-level social fragmentation during childhood would predict more maladaptive core schemas. Additionally, we hypothesized this association to be mediated by greater perceived discrimination.