Simulated and experimental phantom data for multi-center quality assurance of quantitative susceptibility maps at 3 T, 7 T and 9.4 T.

Enrique Gustavo Cuña, Hildegard Schulz,Elisa Tuzzi,Laura Biagi,Paolo Bosco,Margarita García-Fontes,Javier Mattos,Michela Tosetti, Jörn Engelmann,Klaus Scheffler,Gisela E Hagberg

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)（2023）

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摘要

Our iron phantom can be used to evaluate the capability of QSM to detect local variations in susceptibility across different field strengths, when using different MR-sequence protocols. The devised simulation method captures the effect of iron clustering in QSM as seen experimentally and could be used in the future to optimize QSM processing pipelines and achieve higher accuracy for local field effects, as also seen in Alzheimer's beta-amyloid plaques.

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关键词

Quantitative susceptibility mapping, MRI, High -field, Quality assurance

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