83. Reinforcement Learning and Risk for Psychosis in a Clinically Diverse Sample of Youth: Computational Analyses and the Role of Depressive vs. Clinical High-Risk Syndromes

Reinforcement learning (RL) impairments have been observed among youth at clinical high-risk (CHR) for psychosis but also among individuals with common psychopathology, including depression. Depressive disorders frequently co-occur with CHR syndromes and may represent an independent risk state for more serious psychopathology in youth. The extent to which RL impairments in young clinical samples reflect psychosis risk, depressive illness, or both remains unclear.