36. Mechanisms via Which Traumatic Stress Leads to Persistent Fear in Male and Female Rats

Dayan Knox,Negin Mohammadmirzaei,Matthew Biddle,Bailey Collins,Xuezhu Cai,Praveen Kulkarni,Khan Hekmatyar, Donna Wood,Sushma Boyapati,Michelle Barth

Biological Psychiatry（2023）

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摘要

PTSD has a higher prevalence rate in women when compared to men. However, mechanisms via which this sex difference manifests are not well understood. The goal of this study was to examine this sex difference within the single prolonged stress (SPS) rodent paradigm of traumatic stress.

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关键词

PTSD, Extinction Learning and Recall, Anterior Cingulate Cortex (ACC), Amygdala, Hippocampus

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