37. Electroencephalographic Microstates During Sleep and Wake in Schizophrenia

Schizophrenia is associated with aberrant connectivity between neural assemblies. This dysconnectivity produces multiple abnormalities in electroencephalographic data collected from people with schizophrenia. Microstate analysis is a technique for modeling electroencephalographic data with a small set of recurring voltage topographies. Several papers have described microstate abnormalities in schizophrenia. However, these studies have only examined resting state data. Sleep spindles are known to be decreased in schizophrenia, which suggests that there may also be sleep-related microstate abnormalities.