Integrating Human Brain Proteomes With GWAS Results to Identify Causal Brain Proteins for the Major Psychiatric Disorders
Biological Psychiatry(2023)
摘要
Major psychiatric disorders such as major depressive disorder (MDD), bipolar disorder, schizophrenia, anxiety disorders, PTSD, and alcohol use disorder affect approximately 25% of the population annually; however, their treatments are effective in only a subset of the patients, highlighting a pressing need for more effective treatments.
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关键词
causal brain proteins,human brain proteomes,gwas results,psychiatric
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