NOV03 for Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction: The Randomized Phase 3 MOJAVE Study

John D. Sheppard, Fred Kurata,Alice T. Epitropoulos, Sonja Krösser,Jason L. Vittitow

American Journal of Ophthalmology（2023）

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摘要

•NOV03 is a preservative-free ophthalmic drop consisting of perfluorohexyloctane.•NOV03 has been investigated in 3 randomized, double-masked, saline-controlled trials.•Patients had dry eye disease associated with meibomian gland dysfunction.•NOV03 was effective in relieving signs and symptoms of dry eye.•NOV03 was well tolerated, with an adverse event profile similar to that of saline.

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meibomian gland dysfunction,dry eye disease,dry eye disease associated

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