The mechanism underlying the remodeling effect of lactoferrin on midpalatal sutures during maxillary expansion and relapse in rats

American Journal of Orthodontics and Dentofacial Orthopedics(2023)

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摘要
•Lactoferrin (LF) enhanced osteogenesis induced by maxillary expansion.•LF-regulated bone remodeling in midpalatal suture via ERK1/2 and OPG-RANKL-RANK.•The osteogenic effect of LF through local injection was greater than intragastric administration.
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