Autoantibodies of inflammatory cytokines as serum biomarkers in OSA patients

Yifei Fang,Jiao Su, Binglu Zhang,Chunling Zhao, Longtao Ji,Feifei Liang, Zhi Wang, Jimin Hao, Yang Meng,Beilei Wei,Yuyang Huang, Liping Dai,Songyun Ouyang

Clinica Chimica Acta（2023）

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摘要

•This is the first study that showed the independent association of OSA with autoantibodies of inflammatory cytokines.•Indirect ELISA was used to detect the expression level of autoantibodies against CRP, IL-6, IL-8 and TNF-α in OSA.•The combination of anti-CRP, anti-IL-6, anti-IL-8 and anti-TNF-α autoantibodies could be used as reliable parameters for OSA screening and severity evaluation.

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