Diagnostic Value of Contrast-Enhanced Ultrasound and Magnetic Resonance in the Diagnosis of Difficult to Determine Renal Tumor by Enhanced CT

Abstract ObjectiveTo analyze and compare the efficacy of contrast-enhanced ultrasound (CEUS) and magnetic resonance (MRI) in the diagnosis of difficult renal tumor with CT. MethodsA total of 136 patients with renal space occupying who received CEUS and MRI in the Second Affiliated Hospital of Kunming Medical University from January 2013 to December 2020 after improved abdominal enhanced CT was difficult to distinguish between benign and malignant patients were retrospectively analyzed. The diagnostic results of the two examination methods were compared with the pathological examination results to analyze the diagnostic efficacy of the two methods.Results61 cases were benign and 75 cases were malignant. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CEUS, MRI and combined examination for the differential diagnosis of benign and malignant renal tumors difficult to be determined by CT were (CEUS:94.42%, 87.69%, 91.18%, 89.33%, 93.44%;MRI:81.63%, 91.84%, 85.29%, 94.67%, 73.77%;MRI+CEUS:94.67%, 93.44%, 92.65%, 94.67%, 93.44%). Comparison of the sensitivity of single and combined CEUS and MRI in the differential diagnosis of benign and malignant renal tumors that were difficult to be identified by CT: χ2=11.34, P =0.001, there was statistical significance; χ2=0.86, P =0.35, there was no statistical significance; χ2=5.73, P =0.02, between MRI and CEUS +CEUS.CEUS with single and combined MRI examination of CT qualitative differential diagnosis of benign and malignant renal tumors ROC curve shows that applied to the differential diagnosis of benign versus malignant tumor CT is qualitative the MRI + CEUS is better than that of CEUS, CEUS is better than that of MRI, the area under the curve comparison(accurate):MRI compar-ed with CEUC no statistical significance (p = 0.26), magnetic resonance imaging (MRI) and CEUS were compared with MRI + CEUS were statistically significant (p = 0.02, p = 0.01).ConclusionBoth CEUS and MRI can be used to distinguish between benign and malignant renal tumors that are difficult to be characterized by CT. However, CEUS alone has more clinical application value in the diagnosis of benign and malignant renal tumors that are difficult to be characterized by CT considering economic effects, indications and side effects.