Phenolic components from the fruits of Solanum xanthocarpum with anti-inflammatory activity.

Two new compounds ( and ), along with thirty-one known compounds (-) were isolated from the fruits of . The structure of isolates was elucidated by analysis of spectroscopic data and the physicochemical methods. Meanwhile, the anti-inflammatory activity of isolates was determined using LPS-induced RAW 264.7 cells. The results of anti-inflammatory assays indicated that most isolated compounds (, , -, , and ) possessed significant nitric oxide (NO) production inhibition in lipopolysaccharide (LPS)-induced RAW 264.7 cells with IC values ranging from 14.33 to 48.55 M.