Defining the Riddle in Order to Solve It: There Is More Than One "Parkinson's Disease".

Tiago F Outeiro,Roy N Alcalay,Angelo Antonini,Johannes Attems,Vincenzo Bonifati,Francisco Cardoso,Marie-Françoise Chesselet,John Hardy, Graziella Madeo,Ian McKeith,Brit Mollenhauer,Darren J Moore,Olivier Rascol,Michael G Schlossmacher,Hermona Soreq,Leonidas Stefanis,Joaquim J Ferreira

MOVEMENT DISORDERS（2023）

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摘要

Accuracy in defining endophenotypes of "typical PD" across these different but interrelated disciplines will enable better definition of variants and their stratification in therapeutic trials, a prerequisite for breakthroughs in the era of precision medicine. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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Parkinson's disease,neurodegeneration,diagnostic criteria,neuropathology,biological definition,biomarker,Lewy body

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