Oral Delivery of Anti-Parasitic Agent-Loaded PLGA Nanoparticles: Enhanced Liver Targeting and Improved Therapeutic Effect on Hepatic Alveolar Echinococcosis.

Jun Li,Yangyang Yang,Xiumin Han,Jing Li,Mengxiao Tian,Wenjing Qi, Huniu An,Chuanchuan Wu, Yao Zhang,Shuai Han,Liping Duan,Weisi Wang,Wenbao Zhang

International journal of nanomedicine（2023）

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摘要

Our findings demonstrate the advantages of encapsulating H1402 into PLGA nanoparticles and highlight the potential of H1402-NPs as a promising liver-targeting therapeutic strategy for hepatic AE.

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关键词

alveolar echinococcosis,Echinococcus multilocularis,PLGA,nanoparticles,liver targeting,oral administration

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