Tumor microenvironment as a bioreactor for Au&Fe3O4-DNA complex synthesis and targeted cancer therapy

Yi Han Wang,Ke Huang,Zhao Jian Qin,Hong Jie Xiong,Teng Fei Liu,Ting Ya Wang, Xiang Dong Lai,Xiao Hui Liu,Hui Jiang,Xue Mei Wang

Chemical Engineering Journal（2023）

引用 2|浏览4

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摘要

•Multifunctional Au&Fe-DNA complex built in tumor microenvironmental bioreactors.•The complex triggers the regulation of intracellular ROS and GSH levels.•Tumor treatment with targeted localization, apoptosis activation, and photothermal therapy.•No apparent healthy risks during in vivo treatment.

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关键词

Bioreactor,Au &amp,Fe 3 O 4-DNA complex,ROS,GSH,Photothermal therapy

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