Multiple Tumorous Lesions of The Pituitary Gland

Abstract Multiple tumorous lesions with an adenoma make up 1.4 % (232 cases) in the large collection of the German Registry of Pituitary Tumors. 2.0% of all PitNETs are associated with a second lesion. Within the selected cases synchronous multiple pituitary neuroendocrine tumors (PitNETs) account for 17,3%, PANCH cases for 14.7%, PitNETs and posterior lobe tumors for 2.2%, PitNETs and metastases for 5.2%, PitNETs and mesenchymal tumors for 2.6%, PitNETs and cysts for 52.2% and PitNETs and primary inflammation for 6.0%. The mean patient age was 53.8 years with a standard deviation of 18.5 years. 55.3% of the patients were female and 44.7% were male. From 1990 to 2018 there was a continuous increase in the number of multiple tumorous lesions.