Protein corona alters the mechanisms of interaction between silica nanoparticles and lipid vesicles

We investigate the impact of a bovine serum albumin corona on interactions between silica nanoparticles (SNPs) of two different sizes and giant lipid vesicles. The protein corona alters the morphological response of vesicles to SNPs, demonstrating that a protein corona can change the interaction mechanism between nanoparticles and lipid membranes.