Radiofrequency ablation, a potential cure for Tumour-Induced Osteomalacia; Case reports of short and long-term outcomes

Abstract Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by FGF23-secreting tumours. Although typically benign, TIO may result in severe pain and disability. Surgical resection has been the traditional management however, due to tumour location, even some small lesions may require major surgery. Radiofrequency ablation (RFA) provides an alternative to surgery and offers the potential for cure of lesions not easily amenable to surgical resection. We describe the short- and long-term outcomes of three patients following RFA. CT-guided RFA has the potential to cure TIO and should be considered appropriate first-line management for suitable lesions.