The EnvZ/OmpR Two-Component System Regulates the Antimicrobial Activity of TAT-RasGAP _317-326 and the Collateral Sensitivity to Other Antibacterial Agents

Maria Georgieva,Tytti Heinonen,Simone Hargraves,Trestan Pillonel,Christian Widmann,Nicolas Jacquier

Microbiology Spectrum（2022）

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摘要

Antimicrobial peptides (AMP) are promising alternatives to classical antibiotics in the fight against antibiotic resistance. Resistance toward antimicrobial peptides can occur, but little is known about the mechanisms driving this phenomenon.

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The EnvZ/OmpR Two-Component System Regulates the Antimicrobial Activity of TAT-RasGAP 317-326 and the Collateral Sensitivity to Other Antibacterial Agents

The EnvZ/OmpR Two-Component System Regulates the Antimicrobial Activity of TAT-RasGAP _317-326 and the Collateral Sensitivity to Other Antibacterial Agents