Synthesis, characterisation and antimicrobial evaluations of acetyloxyphenyl-1,2,3- triazolotetramethyl hexahydroacridinediones

Tetramethyl-10-(2-hydroxyphenyl)-hexahydro acridinediones were treated with chloroacetyl chloride to give 10-(2- chloroacetyloxyphenyl)hexahydro acridinediones, which were treated with NaN3 in acetone followed by reaction with DMAD yielded tetramethyl-10-[2-(1-triazolo-4,5 dicarboxymethyl)acetyloxyphenyl]-3,4,6,7,9,10-hexahydro1,8-(2H,5H)-acridinediones. All the derivatives were screened for antimicrobial activity.