Important functional role of the protein osteopontin in the progression of malignant pleural mesothelioma.

Elisabeth Digifico,Marco Erreni,Laura Mannarino,Sergio Marchini,Aldo Ummarino,Clément Anfray,Luca Bertola,Camilla Recordati,Daniela Pistillo,Massimo Roncalli,Paola Bossi,Paolo Andrea Zucali,Maurizio D'Incalci,Cristina Belgiovine,Paola Allavena

Frontiers in Immunology（2023）

引用 0|浏览0

暂无评分

摘要

These results demonstrate that OPN is an endogenous growth factor for mesothelial cells and inhibition of its signaling may be helpful to restrain tumor progression . These findings have translational potential to improve the therapeutic response of human MPM.

查看译文

关键词

osteopontin (OPN),MPM (malignant pleural mesothelioma),immune system and cancer,immunotherapy,novel therapeutic approach

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要