Comparative molecular analysis of two HFpEF/diastolic dysfunction models - in search of a unifying disease mechanism

Kyohei Fujita, Petter Rudbaeck, Antonio Kourieh,Patrick Desmond,Valeria Marrocco,Jordan Blondelle,Matus Sotak, Meenu Rajan,Eric Esteve, Anush Velmurugan,Stephanie Myers, Yunghang Chan,Madison Clark,Matthew Wright,Yusu Gu,Nancy Dalton,Majid Ghassemian,Matthew Klos,Emma Borgeson,Kirk Peterson,Stephan Lange

Journal of Molecular and Cellular Cardiology（2022）

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摘要

Despite progress in the molecular analyses of Heart Failure with preserved Ejection Fraction (HFpEF), it remains unclear if the syndrome represents many diseases that manifest themselves with similar phenotypes, or if there is an underlying unifying pathway responsible for the disease etiology.

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hfpef/diastolic dysfunction models

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