1659TiP A Spanish observational study for MOLecular characterization of THYroid carcinoma: MOLTHY Project – TTCC-2020-02

N. Baste Rotllan, J. Martinez Trufero, C. Alvarez Escola,T. Alonso Gordoa,E. Gallardo Diaz, J. Rubió-Casadevall, C.M. Vila,M. Plana Serrahima, A.J. Cunquero Tomas,C. Lopez Lopez, A.A. Segura Huerta,J. Hernando Cubero,M. Durán, C. Teixido, E.M. Ortega Izquierdo, R.M. Regojo, I. Ruz-Caracuel, T. Bonfill Abella, J.J. Grau,R. Mesia Nin

Annals of Oncology(2022)

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摘要
Thyroid cancer (TC) is the most frequent endocrine cancer. Treatment is generally based on surgery +/- radioactive iodine (RAI) and TSH suppression in Differentiated TC (DTC) and surgery and levothyroxine suppression in Medullary TC (MTC). Multiple kinase inhibitor drugs have become the standard therapy for advanced TC. New molecular-driven alterations therapies have raised such as neurotrophic tyrosine kinase receptor (NTRK) and rearranged during transfection (RET) inhibitors. The availability of molecular profiling test at cancer centers provides precision medicine in clinical routine and new treatment opportunities.
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关键词
thyroid carcinoma,molecular characterization
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