White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases.

Research Square (Research Square)(2023)

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摘要
In participants with neurodegenerative and cerebrovascular diseases, our results suggest that smaller cortical thickness and white matter hyperintensity burden in several cortical-subcortical structures may contribute to the development of NPS. Further studies investigating the mechanisms that determine the progression of NPS in various neurodegenerative and cerebrovascular diseases are needed.
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关键词
White matter hyperintensities, Cortical thickness, Neuropsychiatric symptoms, Neurodegenerative disease, Cerebrovascular disease
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