Providing patient-centered care for patients with multidrug- or rifampicin-resistant tuberculosis in Wuhan, China

Abstract Aim: This study was conducted to determine the impact of patient-centered care (PCC) on treatment adherence and outcome of patientswith multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB). Background: Treatment adherence is critical to successful outcomes of MDR/RR-TB. However, very few studies published had addressed how to improve it. Methods: This study retrospectivelyanalyzed treatment outcomes of MDR/RR-TB patient with two different kinds of care: clinical care for group A and PCC for group B. Results: There were 128 patients were assigned in group A and 155 patients in group B. Patients in group B achieved a higher rate of negative 6-month sputum culture conversionthan those in group A (81.6% versus 95.3%, P = 0.0141). The treatment success rates of group A and B were 46.9% versus 68.4% (P = 0.0003), while failure, death, and default rates were4.7%, 9.4%, and 39.1% in group A, versus 1.3% (P = 0.1751), 12.9% (P = 0.3509), and 17.4% (P = 0.0000) in group B, respectively. Conclusions: The PCC promoted MDR/RR-TB patients’ adherence and improved treatment outcomes.