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In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-MPro inhibitors

Ateyatallah Aljuhani,Hany E. A. Ahmed,Saleh K. Ihmaid,Abdelsattar M. Omar,Sultan S. Althagfan,Yaser M. Alahmadi,Iqrar Ahmad,Harun Patel,Sahar Ahmed,Mohannad A. Almikhlafi,Ahmed M. El-Agrody,Mohamed F. Zayed,Safaa Abdulrahman Turkistani,Shorouk H. Abulkhair,Mohammed Almaghrabi,Samir A. Salama,Ahmed A. Al-Karmalawy,Hamada S. Abulkhair

RSC Advances（2022）

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摘要
An essential target for COVID-19 is the main protease of SARS-CoV-2 (Mpro).
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关键词
pyridopyrrolopyrimidines,inhibitors,carboxamide-linked,sars-cov
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