Disseminated Scedosporium Invasive Fungal Infection in Critically ill Newly Diagnosed Acute Myeloid Leukemia Patient Complicated with Cerebritis

Abstract A 66-year-old man presented with fatigue and fever. He was in excellent health status, with no comorbidity, working as a gamekeeper. Blood count revealed 80 G/L leukocytes, 84% blasts, hemoglobin 10.5 g/dL and platelets 27 G/L. He was hospitalized in intensive care unit (ICU) because of oxygen requirement and acute renal failure due to tumor lysis syndrome. Acute myeloid leukemia (AML-5b) with complexe karyotype was diagnosed on bone marrow examination. After initial cytoreduction with Hydroxyurea and Dexamethasone, intensive chemotherapy (Idarubicine and Cytarabine) was initiated in the ICU under close monitoring. Extra-renal epuration was required for tumor lysis syndrome.