Omics approaches in COVID-19: An overview

COVID-19 caused by the virus SARS-CoV2 exhibits its devastating consequences worldwide in terms of health and economic loss. SARS-CoV2 is a novel coronavirus whose mechanism of infection and development of symptoms in patients leading to mortalities are poorly understood. Although primarily a respiratory virus, people infected with SARS-CoV2 show a series of symptoms involving multiple human organs including cardiac abnormalities, neuronal dysfunction, etc. Developing effective drugs to control the pandemic is overwhelmingly important and urgent. Ongoing rigorous scientific research based on molecular biology, genetics, genomics, proteomics, and informatics are in progress to develop suitable therapy. Using the omics-based approach, the correlation of vast amount of COVID-19 patient-related experimental data with patient-specific medical information is necessary prerequisite to manage COVID-19 patients and develop successful therapy especially in rural and urban areas where access to proper healthcare is limited. Conclusive data of these coordinated approaches would immensely help to manage a large number of critically ill patients to improve the treatment outcome and reduce mortalities.