Study of specific properties of Polygonum Aviculare L. dry extract as a hemostatic agent

Journal of Pharmaceutical Negative Results(2022)

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摘要
Polygonum aviculare L., has been used in traditional medicine for many years. Hemostatic activity of the Polygonum aviculare L. dry extract (PADE) on the duration and amount of bleeding was studied in the current research. Moreover, the effect of the PADE was investigated on platelet count and capillary permeability. The results showed that the PADE administration increased platelet count by 212%, decreased retraction time by 50% and increased adhesive capacity by 225% and significantly reduced capillary permeability in the experimental animals. According to the results of this experiment, the Polygonum aviculare L. dry extract can be recommended to use in medical practice as a hemostatic agent in various hemorrhages.
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dry extract
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