Mucus Plugging and Regional Heterogeneity are Features of Asthmatic Small Airways

Stephen Schworer,Kenichi Okuda,Hong Dang,Rodney Gilmore,Wanda O'Neal,Scott Randell,Sally Wenzel,Richard Boucher

Journal of Allergy and Clinical Immunology（2023）

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摘要

Mucus plugging in asthmatic airways contributes to airway obstruction in both mid-size and small airways. Although small airway dysfunction is associated with asthma exacerbations and poor symptom control, the molecular pathophysiology of mucus plugging in small airways is poorly understood.

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