Impact of Salvage Surgery and Re-irradiation for Radiation Failed Recurrent Skull Base Meningiomas

Introduction and Objective: Long-term follow-up of meningiomas has demonstrated recurrence rates of up to 60% after 15 years. There is limited data available to guide the management of recurrent and previously radiated skull base meningiomas and challenges related to salvage surgery, reirradiation and lack of clear systemic therapy strategies remain. In this study, we analyzed data from our experience with recurrent and previously radiated meningiomas to assess the impact of salvage surgery and reirradiation on PFS.