MRI-Guided Stereotactic Craniotomy to Set the Diagnosis of CNS Cryptococcosis. Case Report and Review of the International Literature

Cryptococcosis - a fungal infection - mainly caused by Cryptococcus Neoformans and Cryptococcus Gattii, may affect human central neural system (CNS) with various clinical manifestations. Diagnosis is usually confirmed by direct CSF microscopic examination for encapsulated yeasts by India ink preparation. However, sometimes laboratory tests may not be indicative and brain imaging with biopsy is necessary to reveal the cause in order to offer the adequate beneficial treatment to patients. We present a case of Cryptococcosis diagnosed by our department while reviewing the international literature.