Armoring a liposome-integrated tissue factor with sacrificial CaCO₃ to form potent self-propelled hemostats

Chengkun Liu,Zhuang Shi,Jingyan Zhu,Chang Liu,Xiaodan Liu,Naseer Ullah Khan,Shihai Liu,Xiaojuan Wang,Xiaoqiang Wang,Fang Huang

Journal of Materials Chemistry B（2023）

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摘要

A self-propelled nanoparticle system composed of a tissue factor (TF) integrated into a liposome and a CaCO3 shell was developed, showing superior hemostatic capacity by delivering the lipidated TF deep into bleeding wounds with good biocompatibility.

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关键词

tissue factor,sacrificial caco<sub>3</sub>,liposome-integrated,self-propelled

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Armoring a liposome-integrated tissue factor with sacrificial CaCO3 to form potent self-propelled hemostats

Armoring a liposome-integrated tissue factor with sacrificial CaCO₃ to form potent self-propelled hemostats