260MO Liquid biopsy NGS test identifies actionable DNA mutations from CSF specimens of lung cancer patients

D. Chan,T.M. Chin, J. Chia,Y.C.J. Li, J.W-H. Tsang, J. Poh,C.W. Wong,M-H. Tan

Annals of Oncology(2022)

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摘要
Lung cancer is one of the top causes of cancer death. Liquid biopsies have emerged as a non-invasive method to identify patients who may respond to therapy, enabling dynamic monitoring of minimal residual disease and drug resistance. While plasma specimens have commonly been used for liquid biopsies, we validated the use of cerebrospinal fluid (CSF) for liquid biopsy next-generation sequencing (NGS) testing.
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关键词
lung cancer,lung cancer patients,actionable dna mutations,csf specimens
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