Time resolved SPAD micro-camera probe for wide-field FLIm in microendoscopy

Dario Angelone,Sanathana Konugolu Venkata Sekara, Walter Messinaa,Andrew B. Matheson,Ahmet T. Erdogan,Robert K. Henderson,Ray Burke,Stefan Andersson-Engels

Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI（2022）

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摘要

We propose a handheld single photon avalanche diode (SPAD) micro-camera probe for wide-field in-vivo fluorescence lifetime imaging (FLIm) applications. The presented probe includes a novel 3D stacked 1.4mm x 1.4mm SPAD array, an integrated excitation light source, and imaging optics. The spatial and temporal performance of the integrated system was characterised using a USAF test target and range of fluorescence lifetime beads.

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关键词

fluorescence lifetime imaging, FLIm, SPAD, micro-camera

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