EE641 Economic and Health-Related Quality of Life Consequences of Imaging and Surveillance Schedule in Seminoma Testis

Monitoring with regular computed tomography (CT) is an effective means of identifying relapse in patients treated for stage I seminoma testis; however, risks of radiation exposure are a major concern in these young patients, many of whom won’t relapse. The TRISST randomized trial assessed whether a reduced CT or Magnetic Resonance Imaging (MRI) schedule could be effective alternatives to standard CT-based surveillance. It found that fewer CTs or MRIs were non-inferior in terms of clinical outcomes. This study used the TRISST trial data to evaluate the health care resource consequences and health-related quality-of-life of different surveillance strategies in patients with seminoma testicular cancer in the UK.