#6389 early weight loss after bariatric surgery in patients with organ failure or transplantation

Abstract Background and Aims Obesity is an epidemic that complicates global health and economies. Surgery for obesity (OS) is one effective treatment that results in significant weight loss. Patients with chronic organ failure who are obese undergo OS but it is unknown whether they achieve similar weight loss response as patients who do not have organ failure. Method Patient records of OS cases between May 2016 and June 2022 from a large healthcare system were examined to review weight changes after OS by whether the patient was a transplant patient or not. The proportion of excess weight lost was determined for 1month, 3months, 6months and 1year post OS. Non-parametric analyses were performed; p <0.05 was considered significant. Results of 1,673 OS cases, the mean (SD) age was 47.6 (12.5) years, the majority were female (1,276, 76.3%), and 58% identified as Caucasian. Within this number, 92 patients were transplant candidates (n=50, 3%) or recipients (n=42, 2.5%). The transplant patients were older [51.5 (10.8) years vs 47.3 (12.6) years, P = .0008], had similar body weight [124.4 (22.5) kg vs 126.0 (27.2) kg, P = .8271] but a lower body mass index [42.6 (5.7) kg/m2 vs 45.1 (8.1) kg/m2, P = .0046] compared to patients who were not having a transplant. Transplant patients experienced different weight loss in the early post-operative period but similar weight loss after OS as non-transplant patients (Table 1 and Table 2). Conclusion Though early post-operative differences were noted in this study, patients with organ failure responded similarly to OS as patients without organ failure.