Transarterial chemoembolization with or without multikinase inhibitors for patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis of randomized controlled trials.

Han Dong, Dongfang Ge,Biao Qu,Ping Zhu,Qibiao Wu,Tianyun Wang,Jue Wang,Zheng Li,

Frontiers in Oncology（2023）

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摘要

TACE+MKI combination therapy improved TTP and ORR but not OS and PFS in patients with unresectable HCC. Further high-quality trials are needed to verify these clinical benefits, and our findings could be very informative for future trial design.

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关键词

transarterial chemoembolization,multikinase inhibitor,combination therapy,unresectable hepatocellular carcinoma,meta-analysis

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