Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T

MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE(2023)

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摘要
Object Lower-field MR is reemerging as a viable, potentially cost-effective alternative to high-field MR, thanks to advances in hardware, sequence design, and reconstruction over the past decades. Evaluation of lower field strengths, however, is limited by the availability of lower-field systems on the market and their considerable procurement costs. In this work, we demonstrate a low-cost, temporary alternative to purchasing a dedicated lower-field MR system. Materials and Methods By ramping down an existing clinical 3 T MRI system to 0.75 T, proton signals can be acquired using repurposed 13 C transmit/receive hardware and the multi-nuclei spectrometer interface. We describe the ramp-down procedure and necessary software and hardware changes to the system. Results Apart from presenting system characterization results, we show in vivo examples of cardiac cine imaging, abdominal two- and three-point Dixon-type water/fat separation, water/fat-separated MR Fingerprinting, and point-resolved spectroscopy. In addition, the ramp-down approach allows unique comparisons of, e.g., gradient fidelity of the same MR system operated at different field strengths using the same receive chain, gradient coils, and amplifiers. Discussion Ramping down an existing MR system may be seen as a viable alternative for lower-field MR research in groups that already own multi-nuclei hardware and can also serve as a testing platform for custom-made multi-nuclei transmit/receive coils.
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关键词
Magnetic resonance imaging, Cine MRI, Multiparametric MRI, Technology assessment, Field strength
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