Ischemic Reperfusion Injury After Liver Transplantation: Is There a Place for Conservative Management?

Ischemic reperfusion injury (IRI) after liver transplantation is a com-mon cause of early allograft dysfunction with high mortality. The pur-pose of this case report series is to highlight an unusual clinical course in which complete recovery can occur following the identification of severe hepatic IRI post-transplantation and the implications of this finding on management strategies in patients with IRI post-transplant. Here, we include three cases of severe IRI following liver transplanta-tion that are putatively resolved without retransplantation or defini-tive therapeutic intervention. All patients recovered until their final follow-up visits to our institution and developed no significant com-plications from their injury throughout the course of patient care by our institution after discharge from the hospital.