The effects of kinesiotherapy in cancer patients with chemotherapy-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is a common treatment-related side effect experienced by cancer patients receiving antineoplastic agents. CIPN cannot be treated effectively with pharmaceutical intervention, and the management of its symptoms includes kinesiotherapy. This is a review of kinesiotherapy programs in cancer patients with CIPN. The programs proposed are usually a combination of aerobic exercises, muscle strengthening exercises, balance/sensorimotor training, or closed kinematic chain and core stability exercises. Overall, kinesiotherapy has been shown to reduce the clinical signs and symptoms caused by the side effects of CIPN, including neuropathic pain and altered sensation, improving the physical performance level, mobility, and balance control of the patients, and enhancing their quality of life. Further research is needed to clarify the underlying mechanisms of the exercise-induced reduction of CIPN symptoms.