Sleep loss potentiates Th17-cell pathogenicity and promotes autoimmune uveitis.

Xiuxing Liu,Yuhan Su,Zhaohao Huang,Jianjie Lv,Chenyang Gu,Zhuang Li,Tianyu Tao,Yidan Liu,Qi Jiang,Runping Duan,Binyao Chen,Rong Ju,Xianggui Wang,Yingfeng Zheng,Wenru Su

Clinical and translational medicine（2023）

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摘要

SL promoted Th17 cells pathogenicity and autoimmune uveitis development, especially through the interaction between Th17 and myeloid cells involving GM-CSF signaling, providing possible therapeutic targets for the SL-related pathological disorders.

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sleep loss potentiates

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