Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

Zi-Chun Chia,Yi-Lun Chen,Cheng-Hsun Chuang,Chou-Hsun Hsieh,Ya-Jyun Chen,Kuan-Hsu Chen,Tzu-Chi Huang,Mei-Chin Chen,Chih-Chia Huang

CHEMICAL COMMUNICATIONS（2023）

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摘要

3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 10(2) CFU cm(-2) for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.

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关键词

polylactic acid microneedles,antibacterial photodynamic therapy,photodynamic therapy,polyphenol-assisted,au-deposited

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