Lycopene alleviates oxidative stress-induced cell injury in human vascular endothelial cells by encouraging the SIRT1/Nrf2/HO-1 pathway.

Clinical and experimental hypertension (New York, N.Y. : 1993)（2023）

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摘要

Lycopene alleviates HO-induced oxidative damage in human VECs by reducing intracellular ROS levels, inflammatory factor production, cell adhesiveness, and apoptosis rate under oxidative stress conditions through activation of the SIRT1/Nrf2/HO-1 pathway.

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关键词

Cardiovascular disease,lycopene,oxidative stress,the SIRT1,Nrf2,HO-1 pathway,apoptosis

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