Association of aPTT-Guided Anticoagulation Monitoring with Thromboembolic Events in Patients Receiving V-A ECMO Support: A Systematic Review and Meta-Analysis.

Sasa Rajsic,Robert Breitkopf,Benedikt Treml,Dragana Jadzic,Christoph Oberleitner,Ulvi Cenk Oezpeker,Nicole Innerhofer,Zoran Bukumiric

Journal of clinical medicine（2023）

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摘要

Despite the tremendous development of critical care, aPTT-guided systemic anticoagulation is still the standard monitoring tool. We did not find any association of aPTT levels with thrombosis. Further evidence and new trials should clarify the true incidence of thromboembolic events, along with the best anticoagulation and monitoring strategy in veno-arterial ECMO patients.

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关键词

activated partial thromboplastin time,aPTT,adverse events,anticoagulation,bleeding,cardiogenic shock,extracorporeal life support,ECMO,monitoring

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