Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway.

Shan Wu,Fei Wen,Xiangbin Zhong,Wenjing Du, Manlian Chen,Junyi Wang

Annals of Medicine（2023）

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摘要

Together, our findings indicated that AS-IV exert the hepatoprotective effect by modulating the gut microbiota imbalance and regulating NLRP3/Caspase-1 signaling pathway.

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关键词

Alcoholic liver disease,astragaloside IV,hepatoprotective effect,NLRP3 inflammasome,gut microbiota

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