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Efficient Conversion of a Nonselective Norepinephrin Reuptake Inhibitor into a Dual Muscarinic Antagonist−β2-Agonist for the Treatment of Chronic Obstructive Pulmonary Disease

Rachel Osborne,Nick Clarke,Paul Glossop,Amy Kenyon, Hao Liu,Sheena Patel,Susan Summerhill,Lyn H. Jones

Journal of Medicinal Chemistry（2011）

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