Identification of alcohol induced-differential gene expressions in retinol metabolism using transcriptomics

Background and Aims Alterations in retinol metabolism due to alcohol may have pathophysiological effects in alcohol-associated liver disease (AALD). Using a transcriptomics approach, we aimed to identify alcohol induced-differential gene expression involved in retinol metabolism in wild-type (WT, acute model) and knock-out (KO) mice with a chronic liver injury (acute-on-chronic injury). Materials and