Noninvasive Imaging-Guided In Vivo Estimation of Photothermal Therapy Using Cancer-Targeted Gold-Solid-Lipid Nanomaterial

Chetna Patnaik,Suditi Neekhra, Shreya Dalvi,Sabyasachi Chakrabarty, B. Pradeep K. Reddy,Rohit Srivastava,Abhijit De

Indian Journal of Medical and Paediatric Oncology（2022）

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摘要

Background: Photothermal therapy (PTT) is a promising cancer treatment modality which employs near-infrared laser on gold-nanomaterials for localized heat-mediated tumor ablation. We estimate PTT effect of a novel CSC-targeted photothermal agent, that is, hyaluronic acid (HA)-tagged gold-solid-lipid nanoparticle (Au-SLN) on breast cancer (BC) cells and xenograft tumors.

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关键词

photothermal therapy,vivo estimation,imaging-guided,cancer-targeted,gold-solid-lipid

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