Martin Silicates as Versatile Radical Precursors in Photoredox/Nickel Dual Catalysis

A cross-coupling methodology is described herein based on the nickel catalyzed connection of an aryl moiety to an alkyl radical, generated by photo-induced single electron oxidation of a silicate formed from Martin spirosilane. Complementary to the other anionic radical precursors in photoredox catalysis, Martin silicates enable the access to highly reactive alkyl radicals directly engageable in smooth Csp2-Csp3 bond formations.